Silvana is the President and Founder of Women Political Leaders (WPL), the worldwide network of women politicians. WPL is an independent, non-partisan and not-for-profit foundation that aims to increase both the number and influence of women in political leadership.

Silvana served as Vice-President of the European Parliament (2009-2011) and Member of the European Parliament (2004-2014).

Before her time in politics, she founded and ran a public affairs consultancy in Brussels, which later merged with a larger US firm. In addition to her work for WPL, Silvana serves on the board of the Council of Women World Leaders, the network of women Presidents and Prime Ministers. She is also a member of the European Leadership Network (ELN), a member of the Global Advisory Network of Apolitical Academy Global and an advisory board member to PINK!. She also works as Senior Advisor to Binance, and is a Venture Partner at Conny&Co. Previously, she was a senior Special Advisor for EY. 2016-2020 Silvana represented the EU in the Executive Committee of W20, an official engagement group of the G20. In 2018 and 2019, she was ranked as one of the 100 most influential persons in gender equality by Apolitical. Silvana is a Young Global Leader Alumni of the World Economic Forum.